Acrosome
During fertilization, a sperm must have to first fuse with the plasma membrane and then penetrate with the female egg cell in order to fertilize with it. Fusing to the eggs cell usually causes little problem, whereas penetrating through the egg's hard shells or extracellular matrix can presents more of a problem to the sperm.
During fertilization, a sperm must have to first fuse with the plasma membrane and then penetrate with the female egg cell in order to fertilize with it. Fusing to the eggs cell usually causes little problem, whereas penetrating through the egg's hard shells or extracellular matrix can presents more of a problem to the sperm. Therefore, sperm cell go through a process called as the acrosome reaction which is the reaction that occur in the acrosome of the sperms as it approaches the egg. The acrosome is like a cap structure over the anterior halves of the sperm's head.
As the sperms approaches the zona pellucida of the eggs, which is necessary for initiating the acrosome reactions, the membrane surrounding the acrosomes fuses with the plasma membrane of the sperm's head, exposing the contents of the acrosome. The contents include surface antigens necessary for binding to the egg's cell membrane, and numerous enzymes which are responsible for breaking through the egg's tough coating and allowing fertilization to occur.[1]
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